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Grants strategy for the newly minted PI

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I’d like to solicit the collective science blogosphere’s opinion on strategy for first grant proposals for the newly minted faculty member.

I learned, back in the day… (ha ha- it cracks me up that I can say that, my teenager would be SO embarrassed)- that the first grant proposal that you submit should be the one for which you have the strongest preliminary data, and that you have published on. This  meant taking the project that you left your postdoc lab with and capitalizing on that data to build your first grant proposal, and had the benefit that you could submit your first grant proposal very shortly after starting your faculty position. We all know how freaking long it takes these days to go through the submission/re-submission process, so I guess I feel like getting an early start at this is critical. But… this approach could have the drawback that newly minted PI is out of the lab writing- basically immediately upon starting their faculty position. They may leave a bunch of new, green personnel, relatively unsupervised for a large block of time at the very beginning- leaving staff without a good foundation.

I realize that this isn’t the only approach to one’s first grant proposal. An alternate approach might be to identify a hot area in the same field, an off-shoot of what you are already doing,  develop the preliminary data for the grant in say the first year or so of one’s faculty position, and submit the first grant after a year or so. This approach might have the benefit that the new PI could take advantage of their single best set of hands (their own!) in the first year and really get an exciting area, and new personnel, off on a solid foundation. The obvious disadvantages are that betting on a publication from this first year, while training new personnel and setting up the lab, seems risky. In addition, by delaying the first submission by one year (or whatever interval) – the clock on the year of waiting in line for review of the first proposal- pushes everything back. Third year reviews come around much more quickly than newly minted faculty can imagine.

What say you all?



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